Less Bloat.
Better Digestion.
Steadier Blood Sugar.
⭐⭐⭐⭐⭐ 1,100+ VERIFIED REVIEWS
Your gut barrier takes a beating every day from stress, processed foods, toxins, and irregular eating habits. When it weakens, you feel it — as bloating, gas, indigestion, cravings, and blood sugar swings. Butyrate restores your gut’s best defense system, the gut lining, so digestion, mood, and energy finally feel balanced again.*
Why Your Gut Barrier Matters More Than You Think
A strong gut lining acts as your body’s first line of defense. A weak one lets irritants and other unwanted microbes leak into the bloodstream — disrupting digestion and metabolic balance.
When your gut barrier breaks down, you may experience:
Bloating after meals
Indigestion or cramping
Intense or frequent cravings
Blood sugar spikes and energy crashes
Food sensitivities
Sluggish digestion
Occasional constipation or diarrhea
These issues aren’t random. They all trace back to your gut barrier integrity, or a lack thereof. The good news is — just like a weak muscle — you can strengthen your gut lining and restore the entire gut ecosystem.
Meet Butyrate — The Fuel Your Gut Is Missing
Butyrate is a short-chain fatty acid your gut should produce naturally. It’s essential fuel for a healthy gut. But with nonstop exposure to environmental toxins, nutrient-depleted food, and stress, it’s no wonder our gut ecosystem is struggling. Without enough Butyrate, your gut barrier weakens… digestion slows… cravings intensify… and your blood sugar becomes harder to regulate.
But when you restore Butyrate levels?
Your gut lining begins to repair — and everything downstream improves.*
DIGESTION
ENERGY
blood sugar balance
Nutrient absorption
Mental clarity
Mood stability
Butyrate is an essential end product of a healthy microbiome. Primarily, it fuels your gut cells, strengthening the gut lining and healing leaky gut.*
Quantity:
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Softgels Supplement
GLUTEN FREE
GLYPHOSATE FREE
NON-GMO
How Butyrate Works In Your Body
1
Rebuilds & Reinforces the Gut Barrier*
Butyrate strengthens tight junctions in the gut lining, helping prevent irritants from leaking through and supporting a healthy microbiome.
2
Supports Smooth, Daily Digestion*
It fuels the cells of your colon, helping digestion feel lighter, smoother, and more regular.
3
Helps Regulate Cravings & Blood Sugar*
Healthy SCFA levels support balanced hunger signals and steadier glucose response — helping curb cravings and mid-day crashes.
4
Keeps the Gut–Brain Axis in Balance*
A healthier gut means a calmer, clearer mind and more stable mood.
Real Customers,
Real Gut Relief
Why Butyrate Works When Other Gut Supplements Don’t
Feel like you’ve tried everything without seeing any results? That’s because other gut supplements try to fix what’s in the gut, instead of addressing the gut itself.
Probiotics add bacteria
Prebiotics feed bacteria
Enzymes break down food
Butyrate targets the root problem: gut barrier integrity.
If the barrier is weak, no amount of probiotics or fiber can fully fix bloating, cravings, or blood sugar swings. You’re still walking around with a leaky gut.Butyrate is the missing piece — the foundation your gut needs before anything else can work properly.*
Strengthen Your
Gut Barrier Today
Feel the difference in bloating, digestion, cravings, and blood sugar support.*
Frequently Asked Questions
Will Butyrate help with bloating and gas?
Yes. Many customers experience less bloating and gas as barrier integrity improves.*
Does this support cravings and blood sugar?
Yes — short-chain fatty acids like butyrate play a key role in regulating hunger cues and glucose response.*
How long until I notice results?
Many feel better digestion within 1–2 weeks. Metabolic improvements and improved gut integrity follow with consistent use.*
Is Butyrate similar to a probiotic?
No, butyrate is NOT bacteria but a short-chain fatty acid (SCFA). It’s made in the lower colon by probiotic bacteria and taken up by the colonocytes, the cells that line the colon. It then becomes an important food for those cells. A lack of good bacteria in the colon, due to antibiotic use for example, can lead to an insufficient supply of butyrate.
Is Butyrate safe for long-term use?
Yes, and supplementing butyrate at recommended doses typically has no side effects. It’s a molecule your gut naturally produces — supplementation simply restores healthy levels.*
Can I take it with other supplements?
Yes. Butyrate pairs well with electrolytes, PC, and other digestive support products if needed.
KEY RESEARCH REFERENCES
Bakshi, J., & Mishra, K. P. (2025). Sodium butyrate prevents lipopolysaccharide induced inflammation and restores the expression of tight junction protein in human epithelial Caco-2 cells. Cellular immunology, 408, 104912. https://doi.org/10.1016/j.cellimm.2024.104912
Pedersen, S. S., Prause, M., Sørensen, C., Størling, J., Moritz, T., Mariño, E., & Billestrup, N. (2023). Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice. International journal of molecular sciences, 24(5), 4533. https://doi.org/10.3390/ijms24054533
Elce, A., Amato, F., Zarrilli, F., Calignano, A., Troncone, R., Castaldo, G., & Canani, R. B. (2017). Butyrate modulating effects on pro-inflammatory pathways in human intestinal epithelial cells. Beneficial microbes, 8(5), 841–847. https://doi.org/10.3920/BM2016.0197
Peng, L., Li, Z. R., Green, R. S., Holzman, I. R., & Lin, J. (2009). Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers. The Journal of nutrition, 139(9), 1619–1625. https://doi.org/10.3945/jn.109.104638
Hamari, N., Blaak, E. E., & Canfora, E. E. (2025). The impact of butyrate on glycemic control in animals and humans: a comprehensive semi-systemic review. Frontiers in nutrition, 12, 1603490. https://doi.org/10.3389/fnut.2025.1603490
Recharla, N., Geesala, R., & Shi, X. Z. (2023). Gut Microbial Metabolite Butyrate and Its Therapeutic Role in Inflammatory Bowel Disease: A Literature Review. Nutrients, 15(10), 2275. https://doi.org/10.3390/nu15102275
Huang, X., Oshima, T., Tomita, T., Fukui, H., & Miwa, H. (2021). Butyrate Alleviates Cytokine-Induced Barrier Dysfunction by Modifying Claudin-2 Levels. Biology, 10(3), 205. https://doi.org/10.3390/biology10030205
Zhang, S., Zhang, Y., Li, J., Wang, X., Zhang, M., Du, M., Jiang, W., & Li, C. (2024). Butyrate and Propionate are Negatively Correlated with Obesity and Glucose Levels in Patients with Type 2 Diabetes and Obesity. Diabetes, metabolic syndrome and obesity : targets and therapy, 17, 1533–1541. https://doi.org/10.2147/DMSO.S434499
Mitrović, M., Stanković Popović, V., Erceg, S., Perišić Mitrović, M., Dobrosavljević, A., Stupar, A., Vuković, P., Zlatković, D., & Svorcan, P. (2025). Exploring the Potential of Oral Butyrate Supplementation in Metabolic Dysfunction-Associated Steatotic Liver Disease: Subgroup Insights from an Interventional Study. International journal of molecular sciences, 26(12), 5561. https://doi.org/10.3390/ijms26125561
Zheng, L., Kelly, C. J., Battista, K. D., Schaefer, R., Lanis, J. M., Alexeev, E. E., Wang, R. X., Onyiah, J. C., Kominsky, D. J., & Colgan, S. P. (2017). Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor-Dependent Repression of Claudin-2. Journal of immunology (Baltimore, Md. : 1950), 199(8), 2976–2984. https://doi.org/10.4049/jimmunol.1700105
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